CAREER PORTAL

Clinical Trial Manager/ Clinical Study Lead

Clinical Trial Manager / Clinical Study Lead
Location: Remote (U.S.)
Type: Contract or Full-Time
Compensation: Competitive, based on experience
Position Overview
We are seeking an experienced Clinical Trial Manager / Clinical Study Lead to oversee the planning and execution of early-phase oncology clinical trials. This individual will provide operational leadership across all aspects of study conduct; ensuring trials are delivered on time, within budget, and in full compliance with regulatory and Good Clinical Practice (GCP) standards.
Key Responsibilities

• Lead cross-functional study teams in the day-to-day execution of clinical trials from start-up through close-out.
• Manage site and vendor oversight, including CROs, laboratories, and other clinical service providers.
• Participate in RFP processes, vendor selection, and contract negotiations; monitor study budgets and financial forecasts.
• Review and contribute to essential study documentation including protocols, informed consent forms, case report forms, and operational plans.
• Oversee site performance, enrollment progress, data quality, and key performance metrics; identify and resolve operational issues proactively.
• Conduct or oversee clinical data review, query management, and listings reconciliation.
• Drive risk identification and implement mitigation strategies to ensure adherence to timelines and quality deliverables.
• Support inspection readiness and participate in internal and external audits.
• Collaborate with cross-functional teams such as Clinical Science, Regulatory, Data Management, and Biostatistics to ensure cohesive trial execution.
• Provide training and operational guidance to study sites, vendors, and internal stakeholders.
• Support the implementation and maintenance of clinical systems (e.g., CTMS, EDC, IRT).
• Occasional travel may be required for investigator meetings or site visits.

Qualifications

• Bachelor’s degree in Life Sciences or related discipline required.
• 6–10 years of clinical operations experience, with a strong focus on oncology and early-phase clinical trials.
• Proven experience managing CROs, vendors, and global study teams.
• Comprehensive understanding of ICH-GCP guidelines and global regulatory requirements.
• Exceptional organizational, analytical, and communication skills.
• Demonstrated ability to lead multiple projects in a fast-paced, collaborative environment.
• Self-motivated, detail-oriented, and adept at problem-solving with minimal supervision.

Estimated Min Rate: $140000.00
Estimated Max Rate: $200000.00


What’s In It for You?
We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh’s network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh’s extensive talent community that will provide you with access to Yoh’s vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include:

• Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
• Health Savings Account (HSA) (for employees working 20+ hours per week)
• Life & Disability Insurance (for employees working 20+ hours per week)
• MetLife Voluntary Benefits
• Employee Assistance Program (EAP)
• 401K Retirement Savings Plan
• Direct Deposit & weekly epayroll
• Referral Bonus Programs
• Certification and training opportunities

Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.

Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Visit https://www.yoh.com/applicants-with-disabilities to contact us if you are an individual with a disability and require accommodation in the application process.

For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.

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