Manager Title Bacteriology Platform Lead
Location Swiftwater, PA USA
Job Family Global Clinical Immunology/Vaccines
About the Job Our Team/ Overview The Scientist for the Bacteriology team will design, develop, qualify, validate, and interpret functional serological assays, including serum bactericidal assays (SBA), to characterize immune responses for clinical studies across a vaccine portfolio. In addition to deep immunoassay expertise, the candidate will provide mentorship and effectively collaborate with Bacteriology lab personnel to perform assigned tasks while ensuring compliance with regulatory agency standards. The candidate will serve as a key technical resource, providing expert representation within the Bacteriology group and on multidisciplinary teams. The ideal candidate will remain current on functional immunological assays specific to bacterial pathogens and embrace the evaluation of new technologies and automation to advance our testing capabilities. This is a laboratory-based role requiring a high percentage of time conducting hands-on experimental work while driving innovation in assay development.
Main Accountabilities Laboratory Operations
- Under direction of management, plan and oversee the day-to-day operations and general activities associated with one or more laboratories/projects.
- Ensure laboratory resources (materials/reagents/equipment/facilities) are maintained to meet assigned objectives.
- Support a quality and compliant testing environment (laboratories, equipment, reagents, training and documentation, methods, personnel).
- Maintain alignment of processes and procedures. Share best practices within team/platform.
- Oversee operational activities of staff working in the laboratory.
- Provide guidance and expert advice to staff on technical issues, safety procedures and regulatory compliance matters within the laboratory. Monitor operations to ensure compliance.
- Ensure that new employees are appropriately trained/on-boarded and familiar with laboratory operational requirements.
- Provide guidance and training for complex functional immunological assays.
- Design, execute and troubleshoot functional immunoassays for bacterial pathogens.
- Interpret, summarize and report complex data sets with clear and concise oral and written communications.
- Serve as an internal subject matter expert on developed assays and demonstrate the ability to educate, train or mentor other team members.
- Perform/support activities to ensure test method life cycle management (documentation, method suitability/trending, maintenance, etc.).
- Support completion of analytical deliverables to meet project milestones.
- Lead and assist in the evaluation of new technologies and automation improvements to support analytical expertise as required.
- Work with internal and external partners in support of collaborative projects.
- Ensure adherence to all applicable quality, corporate, safety, and regulatory requirements.
- May serve as Subject Matter Expert (SME) as required.
- Support departmental quality by ensuring adequate support for documentation, investigation, and closure of quality items including change controls, deviations, and CAPAs.
- To function as technical lead, establish and implement complex functional immunoassays for bacterial pathogens to use as clinical endpoint testing, as well as integration of automation technologies to increase assay throughput and reproducibility.
- This role operates within a regulated laboratory environment where data quality and timeline adherence are critical for vaccine development decisions.
- Key challenges include maintaining assay consistency while implementing automation, managing multiple concurrent projects, and adapting established protocols to different bacterial pathogens.
Education
Experience Specialized degree in biological sciences from an accredited University
Bachelor of Science - + 6yr experience
Master of Science - + 3yr experience
PhD - + 1yr experience
- Demonstrated expertise in functional immunoassays for bacterial pathogens as evidenced by scientific publications and presentations at scientific meetings
- In depth knowledge and hands on experience with serum bactericidal assays (SBA's) using both Human Complement (HC) and Baby Rabbit Complement (BRC) is essential
- Ability to work with viruses, bacteria and potentially infectious samples from humans (BSL-2 or BSL-2+)
- Lead, mentor and train lab staff
- Strong ability to deliver complex objectives under aggressive timelines in a rapidly changing environment
- Excellent technical, critical thinking and communication (oral and written) skills with ability to manage projects and resolve technical problems independently and also work effectively within cross-functional teams
- Be a highly motivated team player with the ability to interact effectively within a multi-disciplinary team
Functional/Technical Skills:
- Expertise in functional immunoassays, especially serum bactericidal assays (SBA's)
- Experience with Human Complement (HC) and Baby Rabbit Complement (BRC)
- Experience in design, execution and troubleshooting of functional immunoassays for bacterial pathogens
- Demonstrated expertise in bacterial culture methods and growth optimization techniques
- Experience with quality systems and processes in a regulated environment
- Experience with LIMS systems, reagent characterization and qualification, laboratory equipment and supplies
Estimated Min Rate: $35.00
Estimated Max Rate: $50.00
What’s In It for You?
We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh’s network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh’s extensive talent community that will provide you with access to Yoh’s vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include:
- Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
- Health Savings Account (HSA) (for employees working 20+ hours per week)
- Life & Disability Insurance (for employees working 20+ hours per week)
- MetLife Voluntary Benefits
- Employee Assistance Program (EAP)
- 401K Retirement Savings Plan
- Direct Deposit & weekly epayroll
- Referral Bonus Programs
- Certification and training opportunities
Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.
Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
Visit https://www.yoh.com/applicants-with-disabilities to contact us if you are an individual with a disability and require accommodation in the application process.
For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.
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